What is the maximum recommended concentration of Nitric Oxide combined with Oxygen for ventilation?

The maximum recommended concentration of Nitric Oxide when used in combination with Oxygen for ventilation is set between 20 to 80 parts per million (ppm). This range is based on clinical studies and guidelines that indicate concentration levels within this bracket can provide therapeutic benefits while minimizing potential toxic effects.

Nitric Oxide is used in certain medical conditions, especially for treating pulmonary hypertension, as it helps to dilate blood vessels in the lungs and improve oxygenation. Exceeding the upper threshold of 80 ppm could lead to adverse effects or toxicity, while concentrations below 20 ppm may not be effective in achieving the desired therapeutic outcomes. The significance of adhering to this concentration range ensures both safety and efficacy in patient care when administering Nitric Oxide in clinical settings.